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Although the biosynthesis of selenocysteine has been characterized as expensive and inefficient, its incorporation into proteins allows biological systems with the ability to execute fundamental chemical functions that are beyond the specialized capabilities of cysteine (263)

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In bacteria, tRNA Tyr identity elements include a G1-C72 base pair, which are inverted in archaea and eukaryotes (C1-G72) (Bedouelle 1990

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