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It targets suppressor of cytokine signaling 1 (SOCS1) to alleviate the suppression of JAK/STAT signaling [44], inhibits the transcription factor ETS1 to increase STAT3 activation, strengthens the prodifferentiation effect of cytokines such as IL-23 and IL-6 [45, 46], and suppresses the epigenetic regulator Jarid2 to directly or indirectly relieve the transcriptional repression of Th17-related genes [47]

Cells 8 (2), 84 (2019)

Cancer 116 , 14991504 (2017)

(2008) [] demonstrated that mercury is able to attach to sulfhydryl groups and render essential enzymes needed for cellular stress responses, protein repair and oxidative damage preventive mechanisms inactive