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Similarly, circadian regulation in proximal tubular cells influences sodium transporter expression and mitochondrial metabolism, while collecting duct principal cells rely on clock genes to control water reabsorption through vasopressin signaling pathways (Pearce et al., 2015)

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Choline helps the liver process and excrete chemical waste products within the body, and its also required for the transport and metabolism of fats and cholesterol, which is vital for the healthy functioning of the liver

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Figure 1 7 Therapeutic advances in metabolic AT dysfunction AT thermogenesis presents a compelling therapeutic avenue for obesity and metabolic disorders