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10.1073/pnas.96.12.7110 Proc

Furthermore, elucidating cell-type-specific signaling pathways among hepatocytes, Kupffer cells, and HSCs should facilitate mechanism-driven approaches that simultaneously modulate autophagy and inflammation

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Interestingly, a link between DNA methylation changes and presence of ROS has been suggested with the finding that increased ROS leads to oxidation of 5mC into 5hmC [62], likely leading to changes in gene expression regulation

In a mans body, male hormones are converted to the female hormone oestradiol, and this happens mainly in fat tissue