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Wound Repair and Regeneration 10(6):369-374

Structurally, tazobactam and sulbactam are quite similar

Base Structure's therapeutic potential to treat Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, other dementias and neurodegenerative diseases, spinal cord injury, traumatic brain injury, and sensorineural hearing and vision loss there is a need in the art for compounds that retain Base Structure's therapeutic activities while possessing optimized pharmacokinetic and pharmacodynamic properties

Neuroanat 169 SpodenkiewiczM.Diez-FernandezC.RfenachtV.Gemperle-BritschgiC.HberleJ

Thus, the N-cyclohexyl moiety likely enables Fer-1 to prevent ferroptosis by promoting the tethering of Fer-1 within lipid membranes, as opposed to influencing the intrinsic antioxidant potential of this molecule