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Tambasco et al., 2018)

Penon-Portmann M, Blair DR, Harmatz P

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In Alzheimers disease, astrocytic dysfunction impairs glutamate clearance via downregulated GLT-1/GLAST and reduces lactate production through decreased lactate dehydrogenase A (LDHA) activity, leading to neuronal energy deficits and exacerbated NMDA receptor excitotoxicity

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