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Keywords: Glutamine metabolism, Cancer, Immune cells, Glutamine antimetabolites, Glutaminase inhibitors Introduction Glutamine is involved in numerous cellular biosynthesis processes, including the creation of proteins, lipids, nucleotides, and amino acids [1]

Following this, the water was removed, and 100 L of a chelating solution prepared with Sodium citrate (acquired from Sigma Aldrich CAS 6132-04-3) and EDTA (acquired from Sigma Aldrich CAS 10378-23-1) were added to the microspheres

Costa DVS, Bon-Frauches AC, Silva AMHP, Lima-Jnior RCP, Martins CS, Leito RFC, Freitas GB, Castelucci P, Bolick DT, Guerrant RL, Warren CA, Moura-Neto V, Brito GAC (2019) 5-fluorouracil induces enteric neuron death and glial activation during intestinal mucositis via a S100B-RAGE-NFB-dependent pathway