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Description

Vitamin B12 is used in the metabolism of fats, carbohydrates, and proteins, and is also required for fatty acid synthesis

Most published research uses injection

(NEJM, 2023) reported that Retatrutide (8mg dose) produced 24.2% mean body weight reduction at 48 weeks in adults with obesity

Freezethaw: Avoid repeated freezethaw cycles of the reconstituted solution, as freezing can denature the protein

5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia

Annual blood tests including serum B12, full blood count, ferritin, vitamin D, and folate are recommended as a minimum for long-term post-bariatric monitoring