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During energy stress, an increased AMP/ATP ratio activates AMPK, which promotes autophagy through multiple mechanisms

TCR activation triggers GSH synthesis, influencing T-cell survival and function, while chronic nitro-oxidative stress depletes GSH, compromising metabolic reprogramming and sustaining aerobic glycolysis

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The imaging principle is to adjust the fluorescence emission intensity by a fast photoinduced electron to achieve the probe turn on under the acidic tumor microenvironment and enhance fluorescent imaging

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