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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4

doi: 10.1111/j.1365-2982.2011.01677.x

Considered those nsSNPs of GSR that were found to be conserved for further analyses

doi: 10.1104/pp.111.175737 36 De SouzaM

Ballard KS, Homesley HD, Hodson C, Presant CA, Rutledge J, Hallquist A, Perree M