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The interaction between the gut immune barrier and these microbes contributes to the GI tract becoming a potential source of chronic inflammation, which is closely associated with gut microecology (174, 175)

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The term "antibody variant" refers to a modified antibody (as opposed to a native or starting antibody) or a biomolecule that is structurally and/or functionally similar to a native or starting antibody, which biomolecule includes some difference in amino acid sequence, composition or structure as compared to the native or starting antibody (e.g., an antibody mimetic)

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