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Nevertheless, increased vitamin B6 intake was not protective against T1D progression in the TEDDY study (131)

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This makes oral supplements even less efficient than they usually are." The Summary I know that's a lot of information to consume in one sitting so here is the executive summary: Oral vitamin supplementation is: Dependent on crossing the cells forming intestinal lining for absorption into the circulation Dependent on an intact intestinal lining which can be easily damaged by stress, alcohol, infections and medications Reliant on specific transporters for each vitamin which are sensitive to alcohol use and are "competitive" as several vitamins try to use the same transporter

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Moreover, due to the precision of the medication delivery, needleless injections can be advantageous in terms of dosage accuracy