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Reactive metabolites (such as ROS and electrophiles) can promote adaptive responses through mitochondrial dysfunction, endoplasmic reticulum stress, or DNA damage, thereby increasing molecular chaperone proteins (Figure 3)

Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction

Tertiary amine modification enables triterpene nanoparticles to target the mitochondria and treat glioblastoma via pyroptosis induction

Many patients feel refreshed and more focused after just one session

However, some nanodrug carriers with diameters of 1100 nm have greater therapeutic and diagnostic significance for GBM[56] (Fig

and oxidative damage biomarkers (malondialdehyde, advanced oxidation protein products, ischemia-modified albumin, oxidized low-density lipoproteins), among others that stand out as oxidative damage biomarkers of lipids, proteins (ischemia-modified albumin, advanced oxidation protein products [7]