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In the United States, the FDA regulates drugs for human use, but vendors selling compounds labelled for research purposes only operate in a grey zone that makes straightforward enforcement difficult

doi: 10.1016/j.est.2019.101038

Month 6: Bloodwork confirm B12 + check methylmalonic acid (MMA) if symptoms present

Additionally, polyol pathway activation in the retina of diabetic rats shows increased lipid peroxidation products and depletion of antioxidant enzymes, suggesting that retinal cells and more specifically neuronal cells might be more prone to oxidative stress induced by the polyol pathway early in diabetes (Ola et al., 2018)

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