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KPV inhibits NF-kB, the master switch for inflammatory gene expression in the body

(PubMed) Ziegler D, Nowak H, Kempler P, Vargha P, Low PA

Cytokine 2011 56 520530

An experiment using human peripheral blood macrophages (M) showed that the intracellular GSH content was dose-dependently increased by treatment of M with cystine, and was increased further by the addition of glutamate (Rimaniol et al

ER stress in Alzheimers disease: a novel neuronal trigger for inflammation and Alzheimers pathology

(2) Numerous immunoinflammatory abnormalities are also seen in people with ME/CFS indicating an activated but dysregulated immune system, including high levels of serum neopterin [13, 95], which is a surrogate marker for increased interferon (IFN) levels [114]