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[47] Conversion of propionyl-CoA to succinyl-CoA involves three reactions: Propionyl-CoA carboxylase (EC 6.4.1.3, biotin-dependent) catalyzes: Propionyl-CoA + HCO 3 + ATP D-methylmalonyl-CoA + ADP + P i Methylmalonyl-CoA epimerase (EC 5.1.99.1) converts D- to L-methylmalonyl-CoA

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