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GSTs are divided into two distinct super-family members: the membrane-bound microsomal and cytosolic family members

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[4] Thanks to the phosphorylation at C-6 and the lack of transporters for phosphorylated sugars, it is no longer necessary to expend energy to retain glucose 6-phosphate inside the cell, despite the large difference between its intracellular and extracellular concentrations

They can help improve skin texture and slightly reduce the appearance of cellulite, but they work best when combined with other treatments