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In contrast to apoptosis, necrosis, and autophagy, ferroptosis is characterized by the build-up of lipid reactive oxygen species (ROS) triggering membrane damage

Secondly, due to the interaction and signal crossing among various components in TME, single-target drugs may not achieve the ideal anti-tumor effect, and the development of multi-target drugs or combination drugs seems to solve this problem

Recently, the hormone fibroblast growth factor 21 (FGF21) has attracted attention as a possible therapeutic agent for the treatment of metabolic disorders, including NAFLD [311]

According to the ongoing Harvard Nurses Health Study, trans fatty acids have been associated with increased risk for coronary heart disease because of the way they negatively impact blood cholesterol levels

Em situaes raras e clinicamente mais graves, como algumas alteraes dos nveis ou de origem gentica, podem surgir complicaes cardacas, que requerem avaliao mdica prioritria

Mitochondrial and oxidative unbalance in placentas from mothers with SARS-CoV-2 infection