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Sun Z, Zhang R, Zhang X, Sun Y, Liu P, Francoeur N, et al

Nov 2019;146(5):3879

Glucose-6-phosphate dehydrogenase enzyme oxidizes glucose-6-phosphate to 6-phosphogluconolactone in pentose phosphate pathway ( HMP shunt)

Medical Disclaimer: This article is for informational and educational purposes only and does not constitute medical advice

ROS also activate microglia and astrocytes via p38MAPK/NF-B and JAK2/STAT3 pathways, inducing pro-inflammatory cytokine production and disrupting the neuronal microenvironment, exacerbating OS and cell death (Linnerbauer et al., 2020