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Key biomarkers, including A42, total tau, phosphorylated tau (p181), and neurofilament light chain (NFL), are pivotal in diagnosing and tracking disease progression

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Obesity inhibited miR-30 expression in adipose tissue macrophages (ATMs), and miR-30 was shown to target Delta-like-4 (DLL4), a Notch1 ligand is associated with ATM inflammation

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