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It is unclear whether these membranes exhibit mTORC2 activity in the cellular setting or contribute to the phosphorylation of mTORC2 substrates

Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer

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37,46,47,51 Notably, the regulatory molecules contributing to exercise-induced physiological cardiac hypertrophy have the potential to exert cardiovascular protective effects

ROS also enhance their proliferation via two mechanisms: either by damaging biological molecules, leading to gene mutation and inflammation, or through abnormal oxidative stress redox signaling, which distorts signaling pathways and drives cancer progression

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