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Nature 333 (6169), 140145

Lipid peroxidation damages sperm membranes, reducing fluidity and motility

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Cdc4 substrates include numerous proteins involved in MAPK signaling that mediate cell cycle arrest in response to pheromone [23, 24, 25, 26], the replication regulator Cdc6 [27], the sirtuin deacetylase Hst3 [28], as well as proteins involved in sister chromatid cohesion [29], regulation of calcineurin [30], and mating-type switching [31]

doi: 10.1021/cb800279q

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