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Notably, we identified VGF (nerve growth factor inducible) as a key regulator of cell hypersecretion, whose expression is controlled by both mTOR-STAT3 and ERK-CREB signaling pathways

Third, most preclinical studies involved mainly male animals, and even in clinical studies mainly male patients

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That trial was published in Obstetrics and Gynecology (2019)

cDNA libraries were constructed by random priming using the High-Capacity cDNA Reverse Transcription Kit (Applied Biosystems) and then used as a template for qPCR amplification with Luna Universal qPCR Master Mixes (New England Biolabs) on an AriaMx cycler (Agilent)

With inputs of experimental isotopologue patterns for metabolite substrates, we then calculated the predicted isotopologue patterns of -Glu-Ser-Gly in the scenarios of two different reaction pathways using the joint probability (Fig