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Avoid over-wrapping

However, excessive NAC administration may paradoxically trigger seizures, potentially due to its modulatory effects on the glutamatecysteine antiporter system

Science 334 , 10811086 (2011)

Without some form of biological stratification, their average benefit across unselected patient populations may not justify these costs

The NICE recommendations tell GPs to consider testing in anyone with one symptom or one risk factor, and to treat early to prevent neurological damage that can become permanent