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It is believed that oxidative stress plays an important role in certain liver diseases

PMID: 30895708 [LoE A] [4] Sinha, R., Sinha, I., Calcagnotto, A., Trushin, N., Haley, J

81 Notably, Wnt5a, a common nonclassical Wnt pathway activator, after secretion by fibroblasts, activates the classic Wnt signalling pathway in AT2 cells and inhibits the transdifferentiation of AXIN2 + AT2 cells with stem cell activity into AT1 cells, thus maintaining the dryness of AT2 cells