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Description

This vulnerability arises because mature RBCs lack nuclei and organelles, such as mitochondria, making them especially prone to OS

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10.1016/S0952-3278(97)90552-4 [PubMed: 9384524] [CrossRef] Harder NHO, Hieronimus B, Stanhope KL, Shibata NM, Lee V, Nunez MV, et al

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doi:10.2174/1871527316666170124165222

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The H-ESI source was operated in positive mode at spray voltage 3,500 or negative mode at spray voltage 2,500 with the following parameters: sheath gas 35 a.u., aux gas 7 a.u., sweep gas 0 a.u., ion transfer tube temperature 320 C, vaporizer temperature 275 C, mass range 70 to 1,000 m/z , full scan MS1 mass resolution of 120,000 FWHM, RF lens at 70% and standard AGC

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The stem cell-sparing cyclophosphamide effect may be related to high levels of aldehyde dehydrogenase associated with bone marrow progenitor cells

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The molecular mechanism involved in maintaining the redox state of GCL is currently unclear

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