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For label-free DSF, 1 mg/mL samples were drawn into capillaries in triplicates

Telmisartan in migraine prophylaxis: a randomized, placebo-controlled trial

Mutant HTT directly attacks the mitochondrial membrane and alters calcium homeostasis (Suzuki et al., 2012), and induces mitochondrial dysfunction by damaging mitochondrial DNA (Yang et al., 2008) mitochondrial fission/fusion mechanisms, and mitochondrial energy metabolism (Song et al., 2011)

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Drug features Drug characteristics play a main role in the risk of DILI, influenced by factors such as chemical structure, molecular weight, and lipophilicity

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