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115 ROS enhance the TGF-/Smad2/3 pathway and induce NF-B activation, collectively suppressing antitumor immunity by inhibiting cytotoxic T cells and NK cells, promoting the expansion of Tregs and MDSCs, and upregulating immune checkpoints like PD-1 and PD-L1

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610,611 Deficiency in glutamine inhibits the activation of mTORC1, subsequently downregulating NKT cell proliferation through mTORC1-c-Myc signaling

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