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[149] FCTC marked a milestone as the first international treaty concerning a global health issue that aims to combat tobacco in multiple aspects including tobacco taxes, advertisement, trading, environmental affects, health influences, etc

Key end-users are primarily individual consumers seeking nicotine delivery without inhalation, predominantly in rural and semi-urban areas where access to cigarettes might be limited or culturally less accepted

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Cigarettes, as tobacco products, deliver nicotine through inhalation, affecting the lungs and cardiovascular system