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4I, J, Chlq could also block the SP-mediated degradation of KEAP1, indicating that the autophagy-mediated pathway was also involved

(PubMed) Orban T, Sosenko JM, Cuthbertson D, et al

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This review emphasizes the importance of monitoring folic acid intake and explores alternative supplements such as 5-MTHF or 5-FTHF, which may mitigate these risks by bypassing MTHFR conversion

On the other hand, in vitro studies carried out in astrocytes have shown that cytokines such as TNF, among others, support the production of neuroprotective mediators [163]