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It is known that the Lrp transcription factor reacts to excess cysteine and induces AlaE, a multifunctional transporter that pumps cysteine out of the cell until its level can be reduced

Niacinamide is a form of Vitamin B3

These technologies have been used to depict the GSH metabolic network, helping researchers to screen new drug targets (such as targets for key enzymes in GSH synthesis or metabolism) and biomarkers (such as GSH-related metabolite markers for disease diagnosis and prognosis assessment)