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Extensive preclinical research shows it influences collagen synthesis, antioxidant defense, and tissue regeneration in cell and animal models

Recent Developments 13

In I/R-AKI, N-myc downstream-regulated gene 2 (Ndrg2) deficiency can reduce oxidative stress and delay renal injury by activating PINK1/1Parkin-mediated mitophagy, but the exact mechanism remains to be investigated further[112]