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Neurological deficits severely affect patients quality of life and impose a significant burden on healthcare systems globally (Feigin et al

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The solution should eventually become completely clear and free of any visible particles

Nature 617 , 386394 (2023)

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Recent statistics show that the incidence of AKI in general hospitalized patients is approximately 1015%, while it can exceed 50% in intensive care units ( In most cases, the integrity of renal parenchyma is compromised by renal tubular dysfunction caused by low perfusion or by direct damage to renal interstitial tissues and cellular functions by toxins ( This review examines the sources of oxidative stress in AKI, the mechanisms by which oxidative stress-induced ER stress contributes to cell death through autophagy and apoptosis, and discusses the potential of antioxidants to alleviate these processes in the treatment of AKI