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Notably, prebiotic therapy has been shown to promote probiotic growth, restoring gut function and alleviating IBD symptoms [44, 45]

Because of its smaller peptide size (~2000 Da), marine collagen offers superior digestibility and rapid uptake, making it ideal for visible results in skin firmness and hydration within weeks

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Additional guidance concerning which amino acid changes are likely to be phenotypically silent are found in Bowie et al., Science 247:1306-1310 (1990)