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The peptide's combined effect of stimulating new collagen production while suppressing matrix metalloproteinase expression (the enzymes that break down collagen) provides a mechanistically rational approach to photoaging that operates through different pathways than retinoids or sunscreen

ISSN 0303-7207

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Histopathological findings revealed preservation of neural architecture, with reduced axonal degeneration, diminished neuronal loss, and limited formation of cystic cavities, suggesting an attenuation of secondary injury processes (12)

Primates also face biomechanical stress from an upright position that cannot be replicated in quadrupedal animal models