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Imaging biomarkers in neurodegeneration: current and future practices

Biotechnol Bioeng 117(5):14261435

You can be eating well, sleeping reasonably, exercising regularly, yet still running chronically low in a mineral your brain depends on to function at its best

Mitochondrial lipid peroxidation was determined using the ratiometric fluorescent probe MitoPerOX (Cayman Chemical, 18798) according to the manufacturers protocol

However, it is important to note that while the high energy demand theory is widely accepted, in vivo evidence directly confirming it as the primary or sole cause of neuronal loss in PD remains incomplete, as other factors such as calcium dyshomeostasis and iron metabolism abnormalities are also intertwined [20, 21]

Glutathione production reduces naturally as we age