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Bertone-Johnson, E

With a half-life of 30 minutes to 2 hours, this peptide provides sustained GHRH receptor activation sufficient to enhance growth hormone secretion patterns over multiple pulse cycles while avoiding the prolonged receptor occupancy that could lead to desensitization or tachyphylaxis

Research by the authors was also supported by the Spanish Ministry of Science, Innovation, and Universities (Ministerio de Ciencia, Innovacin y Universidades, PID2023-152233OB-I00) and the Generalitat of Catalonia: Agency for Management of University and Research Grants (2021SGR00990) to RP