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IL-37 has been shown to inhibit the pyroptosis of damaged acinar cells, a mechanism that appears to be linked to its ability to inhibit the activation of the NLRP3 inflammasome

doi: 10.1038/sj.onc.1201878 21 DworaczekHXiaoW

Gut 69:18071817 Nie K, Ma K, Luo W, Shen Z, Yang Z, Xiao M, Tong T, Yang Y, Wang X (2021) Roseburia intestinalis: a beneficial gut organism from the discoveries in genus and species

A larger spectrum of cancers might utilize this non-mutational pathway to create a reducing environment that enables tumor promotion

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