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SKU: 39825163079
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FAS et al., 2024)

No serious adverse events have been reported in published studies

Mechanistically, sorafenib suppresses system Xc-, which promotes ER stress, GSH depletion, and the iron-dependent accumulation of lipid ROS (Dixon et al., 2014)

It is best to consult with a healthcare provider before use

Then the goal of therapy is (I) to reduce free copper in blood by chelators or zinc and (II) to switch cell toxic Cu into a harmless storage form, e.g., by binding to metallothionein