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This NBC-Los Angeles news story that aired Wednesday also does a good job summarizing concerns

Many of these top themes underscore the findings that the combination of vitamin B1, B6, and B12 enhances neuronal survival, regeneration, maturation, synapsing, and networking to a higher extent than treatment with vitamin B12 alone, as Figure 2, Figure 3, Figure 4 and Figure 5 show

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63 The stomach and liver are considered key sites for digestion and transformation, with dysfunction leading to diseases such as indigestion, flatulence ( Tabkheer-i-Meda ), and ulcers ( Quroh-e-Maida )

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Chronic Inflammation Linked to Metabolic and Heart Disease Chronic inflammation creates a domino effect: It stiffens arteries, triggering high blood pressure and a greater risk of heart attacks and strokes. Cells become more resistant to insulin, making diabetes more likely and harder to control