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doi: 10.1007/s40520-020-01553-9 126

Rather than operating through a single receptor or enzyme, this copper peptide ghk cu influences biological systems through several interconnected mechanismsmost of which have been characterized in vitro and in animal studies, particularly rodent wound-healing and fibrosis models (Pickart & Margolina, 2018)

Overall, the study demonstrates the unique binding and functional profiles of the kratom alkaloids, suggesting potential utility for managing pain, but further studies are needed to follow up on these in vitro findings