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Selank modulates GABAergic and serotonergic pathways to calm anxiety, improve emotional stability, and build stress resilience without sedation or impairment

METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARdelta-dependent pathways in skeletal muscle of mice

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doi: 10.1038/jid.2012.472

It is expressed in different cell types, including macrophages, and the effect of the AGE-RAGE axis causes the expression of inflammatory mediators by these cells