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Salleo, A

The NAC region, enriched in hydrophobic residues, possesses strong amyloidogenic properties and serves as the principal driver of -synuclein aggregation 44

Dysbiosis can lead to the activation of pro-inflammatory pathways, such as the NF-B pathway, which in turn increases the production of cytokines and inflammatory mediators that compromise the BBB (Sanz and De Palma, 2009)

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Vascular endothelial growth factor (VEGF) key factor in normal and pathological angiogenesis

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