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Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis

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To quantify the number of LC3-positive puncta and AO-red fluorescence intensity, 30 cells were recorded in randomly selected fields of view by fluorescence microscopy, and the average fluorescence values were analyzed by Image J

Sub-families of ABC transporters particularly MDR1 can bestow resistance to cytotoxicity and targeted chemotherapy and also have a significant functional transport role in BBB and BCSFB

Beyond its anti-ferroptotic role, AB4 exerts multimodal effectsparticularly in combating inflammationthrough this RAGE-Nrf2 axis

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