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BPC-157 has been observed to downregulate pro-inflammatory cytokines and protect against NSAID-induced tissue damage, while TB-500 may modulate macrophage activity and support immune cell migration

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Moreover, in behavioral assays including the object recognition test (ORT), object location test (OLT), and Y-maze, administration of curcumin at doses ranging from 50 to 100 mg/kg enhanced recognition memory, accompanied by modest anti-inflammatory effects, although no significant changes in neurogenesis were observed [217]

T.gondii lysate also activates innate immunity in mice with colorectal carcinoma CT26 tumor, resulting in decreased tumor growth and levels of the metastatic marker TIMP-1 [126]