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Incretin-based therapies have been associated with a body weight (BW) reduction of 5% in at least half of patients in most randomized controlled trials (RCT) and real-world studies (RWS)

Pancreatitis and gallbladder events have been monitored across the GLP-1 class and remain rare

There are not yet significant clinical trials for these peptides, but some doctors, patients, wellness influencers, and Kennedy have voiced support for opening up the market for these drugs