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Therefore, it is important to characterize the entire chain of the molecular events linking ocular hypertension and RGCs death in order to find the most sensitive and convenient target(s) for neuroprotective therapeutic intervention

In this scenario, MG is a glucose-derivative molecule that putatively connects energetic metabolism and the GABAergic system

These results demonstrate that the expression of NRF2 in the liver is acutely dispensable under GSH-depleted conditions

It also discusses the possible involvement of the retina and molecular biomarkers, specifically Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) and ciliary neurotrophic factor (CNTF) in the pathophysiology of SSD and ASD

However, during the onset and progression of autoimmune diseases, immune cells and parenchymal cells in target organs may undergo various types of programmed cell death, including pyroptosis, autophagy, necrosis, and apoptosis

Association Am Pharm Association 46(3):208209