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MiR-126-5p inhibits PIK3R2 expression, disrupting the PI3K/AKT signaling pathway and further promoting degeneration in endplate chondrocytes [154] (Table 5)

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

Treatment of intervertebral disc degeneration in Wistar rats with mesenchymal stem cells

Cells were harvested by centrifugation at 650 x g for 7 min, and washed twice with Wash Buffer (35 mM HEPES/NaOH pH 7.5, 140 mM NaCl, 11 mM glucose) and once with Extraction Buffer (20 mM HEPES/KOH pH 7.5, 45 mM KOAc, 45 mM KCl, 1.8 mM Mg(OAc) 2 , 1 mM DTT)

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You may experience some pain, itching, redness or swelling at the injection site