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Current research indicates that it is safe for canine use, with potential benefits including enhanced recovery from injuries, support for muscle, tendon, and ligament health, and improved gastrointestinal health

Szabo, E

The clinical titration starts at 0.25 mg weekly and increases every four weeks up to a maintenance dose of 2.4 mg weekly, though some research protocols extend up to 4.5 mg

Similar mechanisms may underlie biomechanical processes occurring in the DRG and the dorsal horn, as BDNF and NMDA are prevalent in all neurons involved in pain transmission