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In the striatum, the global reduction in 5hmC may be attributed to the downregulation of Tet1 , Tet2 , and Tet3 , along with the upregulation of MeCP2 , while in the cortex, it may be related to the downregulation of Tet1 (Wang et al., 2013)

According to a different analysis, the progression to mild cognitive impairment (MCI) can be predicted by a figure of different factors, including the presence of apolipoprotein E4 (ApoE4), paired with the score that links instant recall test and the digits symbol substitution test, as well as indicators of the right hippocampus area on MRI and the thickness and volume of the right entorhinal cortex [86]

Because ferritin is one of the downstream targets of Nrf2 (Sun et al

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